Geomembranes are sustainable materials for sustainable civil infrastructure development. However, there is a dearth of country-specific studies that examined the awareness of construction practitioners on the applications of geomembranes in sustainable civil infrastructure development. This study examined the awareness of construction practitioners in Ghana of the applications of geomembranes in sustainable civil infrastructure development. Structured questionnaire aided data collection from 260 construction practitioners. Data were analyzed using the mean, standard deviation, frequency, percentage, and one-sample T-test. Construction practitioners in Ghana generally demonstrated average awareness of the applications of geomembranes, evidenced by a group mean score of 3.552. Peculiar to this study in Ghana is that geomembranes could be applied as a dampproof membrane in building foundations and waterproof sheets to stop leakages in flat concrete roofs. The findings of this study address the dearth of country-specific literature on the awareness of construction practitioners of the applications of geomembranes in sustainable civil infrastructure development. Specifically, it informs policymakers and industry stakeholders in policy enactment toward the realization of sustainability in infrastructure development.