The research work presented in this paper investigates the effect of interference on wind loads on a tall building (instrumented building) having rectangular cross-sectional shape due to the presence of two interfering buildings close to the instrumented building. The effect of interference on the instrumented building is studied with the variation of height and relative orientation of the interfering buildings with respect to the instrumented building. Wind tunnel experiments are undertaken using five component force balance load cell and the results are reported in the form of X-Y plots. The effect of interference in both shielding as well as enhancing the wind load on the instrumented building, is seen to increase with the increase in the height of the interfering building. Negative drag force is also observed in few cases where shielded part of the instrumented building is large. Value of torsion on the instrumented building is observed to be as high as ten times of that in the isolated case.