This paper combines building information modeling with advanced structural modeling to optimize the design of building components using a life-cycle perspective. A new object-oriented software framework that extends an existing program is presented. It creates information-rich finite element models from industry foundation class files that are exported from building information programs. In addition to models for structural responses, the new components contain models for construction cost, repair cost, environmental impact cost, and human health cost. Random variable objects represent uncertainties in material properties, hazards, and cost models. Similarly, design variable objects represent decisions, such as structural dimensions and materials. All costs are summed and the expected value of this sum is employed as a decision criterion. This paper presents the software framework and a demonstration application.