The ongoing global crises prompt us to envision a world where resources are recirculated to enhance the planet's habitability. Addressing this issue requires a multidimensional approach. In architecture, a significant challenge lies in materiality, spanning from the moment of extraction to the point of demolition. However, bio-based and biomaterials present a valuable opportunity for architects, engineers, and planners to engage more effectively with circular practices, resource generation, and self-decomposition. This article presents findings from an exploration with Sigse, a common plant found in Andean regions, as part of several experimental projects involving bio-based materials conducted by the author and his students. By focusing on bio-based resources, digital design, and fabrication, this research-led project fosters critical inquiries into sustainability, computational methods, material research, circular construction, and green technologies in architecture. The findings are organized into three sections. The first chapter outlines the material research conducted, the second chapter explains the design and fabrication process of panels made with Sigse, and the final chapter presents the results.