With the global trend towards internationalization, there is a need to understand the parameters that determine the success of the multicultural and multi-located teams. This research is intended to explore the performance of multicultural and multi-located teams operating in Egypt and the various managerial approaches required to enhance these teams’ work efficiency. The research employed a qualitative-quantitative experiment on multicultural and multi-located teams in one of the foreign firms operating in Egypt. The groups’ performance was analyzed using Porter’s Model and a framework was proposed. The proposed framework was verified through three phase experiment. The final framework developed included organizational culture, mechanism for staff recruitment, communication, leadership styles and decision making approaches. This framework is intended to assist in enhancing the operation of the multicultural and multi-located design engineering teams in Egypt.